The recipient switches it on in the Mail settings, under Privacy Protection, with the option to protect Mail activity. Because content is loaded whether or not the message is opened, trackers that count every image request show opens that nobody made, and the network address no longer reveals the reader’s location.
HawkOpen recognises these requests by the way Apple fetches the image and by Apple’s network, gives them the category privacy proxy and the rule code R-OPEN-APPLE, and does not classify them as human activity or notify you about them. The protection does not click links, so clicks and replies remain useful signals.